Ingredient monographs · physician-led
What's actually in your pregnancy supplement.
Inside each monograph: what the ingredient is, how it works, what the evidence in pregnancy actually shows, the safe intake ranges, and the safety notes a pharmacist checks before it leaves draft.
botanical
20 entries- Safe
Acerola cherry fruit extract in pregnancy: evidence and safety
Acerola cherry extract is a whole-fruit source of vitamin C that's generally safe during pregnancy at typical food and supplement amounts.
- Avoid
Astragalus root in pregnancy: evidence and safety
Astragalus root is a traditional Chinese tonic herb sold for immune support, and it is one of the clearer avoid entries in this library.
- Evidence summary
Beta-Glucan in pregnancy: evidence and safety
Beta-glucan from yeast, oats, or mushrooms is popular in immune supplements, but it has never been tested in a pregnancy safety study.
- Evidence summary
Bromelain in pregnancy: evidence and safety
Bromelain is the pineapple enzyme, and eating pineapple itself is nothing to worry about in pregnancy since the old myth about it triggering labor isn't.
- Caution
Ceylon cinnamon bark powder in pregnancy: evidence and safety
Ceylon cinnamon, also called 'true' cinnamon, is a long-used culinary spice with less coumarin than the more common Cassia cinnamon.
- Caution
Chicory root inulin in pregnancy: evidence and safety
Chicory root inulin is a prebiotic fiber added to bars, yogurts, and fiber gummies. Trials in non-pregnant adults show it raises stool frequency modestly.
- Evidence summary
Deglycyrrhizinated licorice in pregnancy: evidence and safety
DGL is licorice root with the glycyrrhizin taken out, and glycyrrhizin is the specific compound linked to pregnancy risks like preterm birth.
- Safe
Algae-Based DHA in pregnancy: evidence and safety
Algae-based DHA gives you the same brain-building omega-3 that fish provides, without the mercury or the fishy smell that can turn your stomach.
- Evidence summary
Elderberry extract in pregnancy: evidence and safety
Elderberry extract is a popular immune-support ingredient, but no study has ever tested it during pregnancy.
- Caution
Fennel seed in pregnancy: evidence and safety
Fennel seed used in cooking or an occasional cup of tea is unlikely to pose meaningful risk during pregnancy.
- Safe
Ginger root extract in pregnancy: evidence and safety
Ginger root extract has the strongest pregnancy-specific evidence of any botanical for easing nausea and vomiting, backed by MotherToBaby, ACOG.
- Caution
Lemon balm leaf extract in pregnancy: evidence and safety
Lemon balm has a long history as a calming, mild digestive herb, though pregnancy-specific safety research is still limited.
- Caution
Marshmallow root in pregnancy: evidence and safety
Marshmallow root's slippery mucilage can feel soothing on a scratchy throat or an acid-irritated esophagus, and small lab.
- Caution
Milk thistle in pregnancy: evidence and safety
Milk thistle is a flowering plant whose seed extract, silymarin, is sold for liver support.
- Evidence summary
N-Acetylcysteine in pregnancy: evidence and safety
NAC's real pregnancy research comes from hospitals giving it as the antidote for acetaminophen (Tylenol) overdose.
- Safe
Peppermint leaf powder in pregnancy: evidence and safety
Peppermint leaf has a long history of easing mild digestive symptoms, and the small 60 mg dose found in multi-ingredient formulas is roughly what you'd.
- Evidence summary
Quercetin in pregnancy: evidence and safety
Quercetin is a natural plant compound found in onions, apples, and tea, and it's sold as a supplement for its antihistamine-like effects.
- Safe
Rose hips in pregnancy: evidence and safety
Rose hips are a whole-food source of vitamin C, naturally concentrated enough that typical amounts in tea, jam.
- Caution
Slippery elm bark in pregnancy: evidence and safety
Slippery elm bark is a gentle, coating herb people use for a scratchy throat or an upset stomach.
- Caution
Spearmint leaf in pregnancy: evidence and safety
Spearmint leaf, taken as tea, is sometimes used as a gentler alternative to peppermint for reflux.
mineral
11 entries- Safe
Calcium citrate in pregnancy: evidence and safety
Calcium citrate is a well-absorbed, generally safe way to help meet your pregnancy calcium needs.
- Caution
Chromium in pregnancy: evidence and safety
Chromium's adequate intake in pregnancy is 30 mcg a day, and standard prenatal formulas sit near that.
- Caution
Copper in pregnancy: evidence and safety
Copper is an essential mineral with a pregnancy RDA of 1,000 mcg a day, and typical diets already land in that range.
- Caution
Iodine in pregnancy: evidence and safety
Iodine is an essential mineral your body uses to make thyroid hormone for your baby's brain and bone development.
- Safe
Iron in pregnancy: evidence and safety
Iron as ferrous bisglycinate is generally considered safe in pregnancy and tends to be gentler on digestion than regular ferrous sulfate.
- Safe
Magnesium glycinate in pregnancy: evidence and safety
Magnesium glycinate is generally considered safe during pregnancy at normal recommended amounts, and it's often gentler on digestion than magnesium oxide.
- Safe
Magnesium in pregnancy: evidence and safety
Magnesium, taken as magnesium oxide, has a pregnancy RDA of about 350 to 360 mg a day and a supplemental upper limit of 350 mg a day beyond food.
- Caution
Manganese in pregnancy: evidence and safety
Manganese is an essential trace mineral, and pregnancy calls for about 2 mg a day, an amount most people already get from grains, nuts, and tea.
- Caution
Potassium in pregnancy: evidence and safety
Getting potassium from everyday food like bananas, potatoes, and orange juice is a normal, safe part of eating well in pregnancy.
- Caution
Selenium in pregnancy: evidence and safety
Selenium is a trace mineral your thyroid depends on, and the pregnancy target is a narrow 60 mcg a day.
- Safe
Zinc in pregnancy: evidence and safety
The recommended amount of zinc during pregnancy is 11 to 12 mg a day, with an upper limit of 40 mg.
supplement
4 entries- Caution
Activated charcoal in pregnancy: evidence and safety
Activated charcoal is a porous carbon powder that binds substances inside the gut. In a hospital it has a genuine role after certain poisonings.
- Evidence summary
Alpha-Lipoic acid in pregnancy: evidence and safety
Alpha-lipoic acid is an antioxidant compound your cells make in small amounts and supplements deliver in much larger ones.
- Evidence summary
Inositol in pregnancy: evidence and safety
Inositol is a sugar alcohol your body makes and your diet supplies, studied in pregnancy at around 4 g a day for blood sugar outcomes.
- Caution
L-Theanine in pregnancy: evidence and safety
L-theanine is an amino acid found in tea leaves and sold as a standalone calming supplement.
vitamin
12 entries- Safe
Biotin in pregnancy: evidence and safety
Biotin is a safe, everyday nutrient, and most pregnant women get enough from food and a prenatal vitamin even though a mild dip in biotin activity is.
- Safe
Choline in pregnancy: evidence and safety
Choline is a brain-building nutrient most pregnant women fall short on, since the daily target is 450 mg and most prenatal vitamins contain little or none.
- Safe
Folate in pregnancy: evidence and safety
Folate is the single most important nutrient to get right in pregnancy. This formula supplies about 1,470 mcg per serving.
- Safe
Pantothenic acid in pregnancy: evidence and safety
Pantothenic acid, or vitamin B5, is a safe everyday nutrient your body uses to turn food into energy.
- Safe
Riboflavin in pregnancy: evidence and safety
Riboflavin, or vitamin B2, is a safe everyday nutrient already covered by most prenatal vitamins.
- Safe
Thiamine in pregnancy: evidence and safety
Thiamine (vitamin B1) is an essential nutrient that most people get enough of through diet and a standard prenatal vitamin.
- Safe
Vitamin B12 in pregnancy: evidence and safety
Vitamin B12 helps build your baby's nervous system and keeps your red blood cells healthy, and most prenatal vitamins already cover what you need.
- Safe
Vitamin B6 in pregnancy: evidence and safety
Vitamin B6 (pyridoxine) is ACOG's first choice for pregnancy nausea and is considered safe up to the NIH pregnancy limit of 100 mg per day.
- Safe
Vitamin C in pregnancy: evidence and safety
The recommended amount of vitamin C in pregnancy is 85 mg a day, with an upper limit of 2,000 mg a day.
- Safe
Vitamin D3 in pregnancy: evidence and safety
Vitamin D3 (cholecalciferol) has a pregnancy RDA of 600 IU a day and a safe upper limit of 4,000 IU a day.
- Caution
Vitamin E in pregnancy: evidence and safety
Vitamin E at the pregnancy RDA of 15 mg a day is well established and easy to get from food.
- Caution
Vitamin K in pregnancy: evidence and safety
Vitamin K from leafy greens and the modest amount in a prenatal is well tolerated, and no upper limit has been set.
