Symptom guide · Pregnancy Smart
Flu-season immune support: second trimester
By trimester
Weeks 14–27
2nd trimester
Getting vaccinated is still the top priority. This is often when people catch up on vaccines if they haven't already gotten them. Your provider may also suggest an intranasal steroid or a second-generation antihistamine on top of basic supportive care.
What does the evidence show for flu-season immune support?
- The flu shot is recommended in any trimester, and many providers use second-trimester visits to catch up on flu, Tdap, and RSV vaccines together. 1
- Pregnant people face a higher risk of severe flu and hospitalization than non-pregnant adults, which is why getting vaccinated now protects both you and your baby. 2
- Intranasal steroids like fluticasone and second-generation antihistamines like cetirizine are broadly acceptable options for congestion or allergy symptoms during pregnancy. 3
- Balanced nutrition, enough protein, and covering key nutrients like vitamins A, C, D, E, zinc, iron, and selenium all support your immune system, and most prenatal vitamins already cover this exact list. 4
- Pregnant women whose flu progresses to pneumonia often show breathing distress, rapid breathing, and pleuritic chest pain, and severe cases carry a higher chance of complications including fetal distress from poor oxygenation and preterm birth. 5
When should I call my provider about flu-season immune support?
Call your provider the same day, or seek urgent care, for trouble breathing or unusually fast breathing, or chest pain that is sharper when you breathe in. Pregnancy raises the chance that a bad case of flu progresses to pneumonia, which can show up as breathlessness, rapid breathing, and pleuritic chest pain alongside a cough. Severe respiratory illness that isn't caught early can lower oxygen delivery to your baby and raise the chance of preterm birth, so these symptoms call for same-day attention rather than home monitoring alone. None of these lists replace your own judgment: if this symptom worries you, that on its own is enough reason to check in with your healthcare provider.
Frequently asked questions
Is the second trimester a better time for the flu shot?
Not necessarily. The CDC recommends the flu shot in any trimester, so there's no reason to wait if it was offered earlier. The second trimester is just when a lot of people end up catching up if they held off before.
Can I take zinc lozenges or extra vitamin C?
Your prenatal vitamin already gives you zinc and vitamin C at pregnancy-appropriate levels. Talk to your provider before adding more, since there isn't much pregnancy-specific evidence that extra amounts help beyond what your prenatal already covers.
What if I've been exposed to someone with the flu?
Call your obstetric provider right away. An antiviral called oseltamivir has been used after flu exposure in some pregnancies, but that's a time-sensitive decision your provider needs to make with you.
Does my partner or older kids getting vaccinated help me?
Yes. When the people around you are vaccinated, your own exposure drops. The CDC recommends this kind of cocooning, vaccinating your close contacts to help protect you.
Related in the library
Ingredients
Vitamin C in pregnancy: evidence and safety
Ingredients
Vitamin D3 in pregnancy: evidence and safety
Symptoms
Flu-season immune support: first trimester
Symptoms
Flu-season immune support: third trimester
Symptoms
Colds during pregnancy
Symptoms
Nasal congestion and pregnancy rhinitis
Is it safe?
Is elderberry safe during pregnancy?
References
Guidelines for Vaccinating Pregnant Women: CDC
CDC · https://www.cdc.gov/vaccines-pregnancy/hcp/vaccination-guidelines/index.html
Flu Vaccine Safety and Pregnancy: CDC
CDC · https://www.cdc.gov/flu/vaccine-safety/vaccine-pregnant.html
Fluticasone (Flovent, Flonase): MotherToBaby Fact Sheet
MotherToBaby · https://mothertobaby.org/fact-sheets/fluticasone-flovent-flonase/
Dietary Supplements for Immune Function and Infectious Diseases: Consumer (NIH ODS)
ODS · https://ods.od.nih.gov/factsheets/ImmuneFunction-Consumer/
Influenza and Pneumonia in Pregnancy
PMC · https://pmc.ncbi.nlm.nih.gov/articles/PMC7119023/
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
