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Is it safe? · Pregnancy Smart

How long before pregnancy should you quit smoking?

Assigned clinical reviewerPerry Friedman· MD, FACOG-MFMDraft · pending clinical reviewUpdated

What does the evidence say about quitting smoking before trying to conceive while trying to conceive?

  1. Cigarette smoke exposure can make it harder to get pregnant, women smoking more than 10 cigarettes a day face a higher infertility risk, and smoking may affect uterine receptiveness in a way that impacts implantation. 1
  2. Miscarriage risk is higher among women exposed to cigarette smoke, and some studies link greater smoke exposure to a higher chance of cleft lip or palate, heart defects, and respiratory or digestive problems in the baby. 2
  3. In a prospective fecundability study, current regular smokers had roughly a 10 percent lower chance of conceiving each cycle than never-smokers, and that gap widened to about 23 percent lower among women smoking 10 or more cigarettes a day for 10 or more years. Former smokers still showed slightly reduced fecundability, with little difference based on how long ago they had quit. 3
  4. Smoking affects fertility in a dose-dependent way: cadmium and a nicotine byproduct that accumulate in ovarian follicular fluid are linked to lower egg quality, and in a pooled analysis of 7 studies, women who smoked needed about twice as many IVF cycles to conceive as nonsmokers. 4
  5. In men, smoking is linked to reduced sperm concentration and movement, and fecundity is described as returning to normal with smoking cessation, which is why cessation counseling is considered an important part of an infertility evaluation even though an exact recovery timeline hasn't been established. 4

What to know about quitting smoking before trying to conceive while trying to conceive

  • There's no proven safe countdown, so the practical move is to quit as soon as pregnancy enters the picture rather than waiting for a specific number of months. Smoking is linked to lower uterine receptiveness, which may affect how well an embryo implants.
  • A partner who smokes matters too. Male smoking is linked to lower sperm concentration and movement, and animal research suggests it can reduce sperm's ability to bind to and fertilize an egg, so quitting works best as a shared plan.
  • If conception is taking longer than expected, know that smokers undergoing IVF have needed about twice as many cycles to conceive compared with nonsmokers in pooled research. Fecundity is described as returning to normal with cessation, so quitting still helps even if you're already several months into trying.

Frequently asked questions

How long does it take for fertility to improve after quitting smoking?

There's no firm, agreed-on number. One large fecundability study found former smokers still had slightly lower odds of conceiving each cycle than people who'd never smoked, without a clear link to how long ago they'd quit. Clinical sources describe fecundity as returning to normal with cessation, just without a guaranteed calendar.

Does smoking affect egg quality or sperm quality?

Yes, both. In women, byproducts of cigarette smoke build up in the fluid around developing eggs and are linked to lower egg quality. In men, smoking is linked to reduced sperm concentration and movement.

Is it too late to quit smoking once you're already trying to conceive?

No. Fecundity is described as returning to normal with cessation, and every cycle without cigarette exposure removes one more variable. Quitting partway through trying still helps, and quitting once pregnant helps more than continuing to smoke.

How does smoking affect male and female fertility differently?

In women, the concern centers on egg quality and implantation, plus a higher risk of miscarriage and certain birth defects if pregnancy happens. In men, the concern centers on sperm concentration, movement, and the sperm's ability to bind to and fertilize an egg. Both partners smoking is linked to needing more IVF cycles to conceive.

Does smoking make IVF less likely to work?

Research pooling several studies found women who smoked needed roughly twice as many IVF cycles to conceive compared with nonsmokers, which is one of the clearer numbers in this area even though a preconception quit-by date isn't established.

References

  1. Cigarette Smoke: MotherToBaby Fact Sheet

    MotherToBaby · https://mothertobaby.org/fact-sheet-reference/cigarette-smoke/

  2. Cigarette Smoke, MotherToBaby Fact Sheet, NCBI Bookshelf

    MotherToBaby · https://www.ncbi.nlm.nih.gov/books/NBK582635/

  3. Prospective Study of Cigarette Smoking and Fecundability

    PMC · https://pmc.ncbi.nlm.nih.gov/articles/PMC6389864/

  4. Environmental Toxins and Infertility, StatPearls, NCBI Bookshelf

    StatPearls · https://www.ncbi.nlm.nih.gov/books/NBK576379/

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.