Is AG1 (Athletic Greens) safe during pregnancy?

What does the evidence say about AG1 during pregnancy?

1. A 12-week randomized, placebo-controlled study of 120 healthy adults measuring complete blood count, comprehensive metabolic panel, and lipid panel found AG1 supplementation did not adversely affect renal, hepatic, or other clinical safety markers, with no adverse events reported in either group. 1
2. A randomized gut-microbiome trial describes AG1 as a synbiotic blend of vitamins, minerals, prebiotics, probiotics, and phytonutrients, and its exclusion criteria specifically ruled out pregnant women, women trying to become pregnant, women less than 120 days postpartum, and nursing women. 2
3. A study in resistance-trained adults describes AG1's formulation as essential vitamins and minerals, fermentable fibers, lactic acid bacterial probiotic strains, and plant-based whole fruit and vegetable powders plus adaptogens, and found it improved several micronutrient adequacy gaps, most often vitamins A, C, and E. 3
4. A broader safety review of adaptogenic botanicals, the category AG1's blend draws several ingredients from, found that most clinical trials focus on whether the products work rather than documenting adverse events, and flagged hepatotoxicity as a recurring concern across multiple adaptogenic products without addressing pregnancy-specific risk at all. 4
5. None of the published clinical trials on AG1's safety, gut-microbiome effects, or nutritional adequacy have enrolled pregnant or breastfeeding participants, so the reassuring safety-marker data these studies report applies only to non-pregnant, non-nursing adults. 2

Is AG1 safe in each trimester?

• First trimester. If you were taking AG1 before pregnancy, flag the full ingredient list to your provider once you find out you're pregnant, since some of its adaptogenic botanicals don't have pregnancy safety data.
• Second trimester. The same approach applies here. A prenatal vitamin covers your core micronutrient needs during pregnancy, so AG1 would be layered on top rather than a substitute, which is another reason to loop in your provider first.
• Third trimester. No pregnancy-trimester-specific research exists on AG1 at any point in pregnancy, so there's nothing new to add beyond the general caution that applies throughout.